Recombinant Varicella-zoster virus Tegument protein UL47 homolog (ORF11), partial

• Abbreviation:

  Recombinant Varicella-zoster virus ORF11 protein, partial

• Gene Name:

  ORF11

• UniProt:

  P09263

• Expression Region:

  354-808aa

• Organism:

  Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3)

• Target Sequence:

  IERILVEDVFLDRRASSKTHKYGPRWNSVYALPYNAGKMYVQHIPGFYDVSLRAVGQGTAIWHHMILSTAACAISNRISHGDGLGFLLDAAIRISANCIFLGRNDNFGVGDPCWLEDHLAGLPREAVPDVLQVTQLVLPNRGPTVAIMRGFFGALAYWPELRIAISEPSTSLVRYATGHMELAEWFLFSRTHSLKPQFTPTEREMLASFFTLYVTLGGGMLNWICRATAMYLAAPYHSRSAYIAVCESLPYYYIPVNSDLLCDLEVLLLGEVDLPTVCESYATIAHELTGYEAVRTAATNFMIEFADCYKESETDLMVSAYLGAVLLLQRVLGHANLLLLLLSGAALYGGCSIYIPRGILDAYNTLMLAASPLYAHQTLTSFWKDRDDAMQTLGIRPTTDVLPKEQDRIVQASPIEMNFRFVGLETIYPREQPIPSVDLAENLMQYRNEILGLDW

• Tag:

  N-terminal 10xHis-tagged and C-terminal Myc-tagged

• Type:

  In Stock Protein

• Source:

  E.coli

• Field of Research:

  Others

• Relevance:

  Tegument protein that can bind to various RNA transcripts. Plays a role in the attenuation of selective viral and cellular mRNA degradation by modulating the activity of host shutoff RNase ORF17/VHS. Plays also a role in the primary envelopement of virions in the perinuclear space, probably by interacting with two nuclear egress proteins ORF24 and ORF27.

• Endotoxin:

  Not test

• Purity:

  Greater than 85% as determined by SDS-PAGE.

• Activity:

  Not Test

• Form:

  Liquid or Lyophilized powder

• Buffer:

  If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

• Reconstitution:

  We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

• Molecular Weight:

  58.3 kDa

• References & Citations:

  "Identification and functional characterization of the Varicella zoster virus ORF11 gene product." Che X., Oliver S.L., Sommer M.H., Rajamani J., Reichelt M., Arvin A.M. Virology 412:156-166 (2011)

• Storage Conditions:

  The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

• Protein Length:

  Partial