Recombinant Sheep P-selectin (SELP)

• Product Name Alternative:

  CD62 antigen-like family member P; CD62P antigen; Granule membrane protein 140; Leukocyte-endothelial cell adhesion molecule 3; Platelet activation dependent granule-external membrane protein

• Abbreviation:

  Recombinant Sheep SELP protein

• Gene Name:

  SELP

• UniProt:

  P98109

• Expression Region:

  33-769aa

• Organism:

  Ovis aries (Sheep)

• Target Sequence:

  LMTQKEVSAWTYHYSDKPYSWNYSRAFCQKYYTDLVAIQNKNEIAYLNETIPYYNSYYWIGIRKIDNKWTWVGTKKTLTEEAENWADNEPNNKKNNQDCVEIYIKSPSAPGKWNDEPCGKRKRALCYRASCQDMSCSKQGECIETIGNYTCSCYPGFYGPECEYVRECGEFDLPQNVHMNCSHPLGNFSFKSQCSFHCAEGYALNGPRELECLASGIWTNSPPQCVAVQCPALKSPEQGSMSCFHSAKAFQHQSSCSFSCEEGFTLVGPEVVHCTALGVWTAPTPVCKAIACESLESPVHGSMDCSPSPRAFQYNTSCSFRCAEGFTLRGADTVRCADSGEWTAPAPVCQALQCQDLPTSNKARVNCSHPFGDFRYQSTCSFTCDEGSFLVGASVLQCLDTGNWDAPFPECQAVTCAPLPNPQNGEKTCVQPLGGSSYKSTCWFTCHEGFSLSGPERLDCTPSGHWTGSPPTCEASKCPELSAPEQGSLDCPDTHGEFIVGSICHFSCNEGLKLEGSNHVECTASGRWTAPPPSCKVDTVSAPAPGLRCPSLIAPNQGTMSCQHHLRNFGLNTTCHFGCKAGFTLMGESALQCRPSRQWTAVAPTCRAVKCSKLPVTEPIVMNCSNPWGNFSYGSTCSFHCPEGQLLNGSERTACQENGQWSTTMPTCQAGPLTIQEALTYIGGAAAGTTGLVTSSILLALLRRRRRQKDDGKSPLNPQSHLGTYGVFTNAAFDPSP

• Tag:

  N-terminal 10xHis-tagged

• Type:

  Developed Protein

• Source:

  E.coli

• Field of Research:

  Others

• Relevance:

  Ca (2+) -dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta-3 (ITGAV:ITGB3)

• Endotoxin:

  Not test

• Purity:

  Greater than 90% as determined by SDS-PAGE.

• Activity:

  Not Test

• Form:

  Liquid or Lyophilized powder

• Buffer:

  If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

• Reconstitution:

  We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

• Molecular Weight:

  86.5 kDa

• Storage Conditions:

  The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

• Protein Length:

  Full Length of Mature Protein