Recombinant Macaca mulatta Interleukin 23 receptor (IL23R), partial

• Product Name Alternative:

  IL23R

• Abbreviation:

  Recombinant Rhesus macaque IL23R protein, partial

• Gene Name:

  IL23R

• UniProt:

  F6XR82

• Expression Region:

  24-353aa

• Organism:

  Macaca mulatta (Rhesus macaque)

• Target Sequence:

  GITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQPRQLHFYKNGIKERFEITRINKTTARLWYKNFLEPHASMYCTAECPNHFQETLICGKDISSGYPPDVPDEVTCVIYEYSGNMTCTWNAGKLTYVDTKYVVHVKSLETEEEQQYLTSSYINISTDSLQGGKKYLVWVQAENALGMEESKQLQIHLDDIVIPSASIISRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATADQTWNVKEFDTNFTYVQQSEFYLEPNIKYIFQVRCQETGKRYWQAWSSPFFHKTPETVPQVTSKSSQHNTWNSGLTVASISTGHLTSDNRED

• Tag:

  C-terminal hFc1-tagged

• Type:

  Developed Protein

• Source:

  Mammalian cell

• Field of Research:

  Others

• Relevance:

  Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis

• Endotoxin:

  Not test

• Purity:

  Greater than 95% as determined by SDS-PAGE.

• Activity:

  Not Test

• Form:

  Liquid or Lyophilized powder

• Buffer:

  If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

• Reconstitution:

  We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

• Molecular Weight:

  65.4 kDa

• Storage Conditions:

  The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

• Protein Length:

  Partial