Recombinant Human Ras-related protein Rab-6A (RAB6A)

• Product Name Alternative:

  GTP binding protein RAB6A'; GTP binding protein RAB6B; Oncogene RAB6; Rab 6; Rab GTPase; Rab-6; RAB6; RAB6 member RAS oncogene family; RAB6A; RAB6A member RAS oncogene family ; Rab6A variant 3; RAB6A'; RAB6A_HUMAN; RAB6B; Ras related protein Rab 6A; Ras-related protein Rab-6A; RCO4 3

• Abbreviation:

  Recombinant Human RAB6A protein

• Gene Name:

  RAB6A

• UniProt:

  P20340

• Expression Region:

  2-208aa

• Organism:

  Homo sapiens (Human)

• Target Sequence:

  STGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVSEGGCSC

• Tag:

  N-terminal 6xHis-SUMO-tagged

• Type:

  Developed Protein

• Source:

  E.coli

• Field of Research:

  Transport

• Relevance:

  Protein transport. Regulator of mbrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER) . Has a low GTPase activity.

• Endotoxin:

  Not test

• Purity:

  Greater than 90% as determined by SDS-PAGE.

• Activity:

  Not Test

• Form:

  Liquid or Lyophilized powder

• Buffer:

  If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

• Reconstitution:

  We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

• Function:

  Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER) . Has a low GTPase activity. Involved in COPI-independent retrograde transport from the Golgi to the ER

• Molecular Weight:

  39.5 kDa

• References & Citations:

  The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.Zahraoui A., Touchot N., Chardin P., Tavitian A.J. Biol. Chem. 264:12394-12401 (1989)

• Storage Conditions:

  The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

• Protein Length:

  Full Length of Mature Protein