Recombinant Human Claudin-18.2 (CLDN18.2) -Detergent

• Product Name Alternative:

  CLDN18; UNQ778/PRO1572

• Abbreviation:

  Recombinant Human CLDN18.2 protein-Detergent

• Gene Name:

  CLDN18.2

• UniProt:

  P56856-2

• Expression Region:

  1-261aa

• Organism:

  Homo sapiens (Human)

• Target Sequence:

  MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKIYDGGARTEDEVQSYPSKHDYV

• Tag:

  N-terminal Flag-tagged and C-terminal Twin-Strep-tagged

• Type:

  MP-Detergent Transmembrane Protein & Developed Protein

• Source:

  Mammalian cell

• Field of Research:

  Signal Transduction

• Relevance:

  Required for the formation of the gastric paracellular barrier via its role in tight junction formation, thereby involved in the response to gastric acidification

• Endotoxin:

  Not test

• Purity:

  Greater than 90% as determined by SDS-PAGE.

• Activity:

  Not Test

• Form:

  Liquid

• Buffer:

  50 mM HEPES, 0.15 M NaCl, 0.05% DDM, 0.01% CHS, pH7.5

• Reconstitution:

  /

• Molecular Weight:

  32.0 kDa

• Storage Conditions:

  The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

• Protein Length:

  Full Length of Isoform A2